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Ultram Generic is an opioid analgesic derived from cyclohexanol. Pharmacological properties of the Ultram medication are determined by the cumulative effect of its constituent components - tramadol and paracetamol. Tramadol is a cyclohexanol derivative with opiate-agonist properties and belongs to centrally acting analgesics. This component has a weak affinity for opiate receptors without preferential selectivity for individual receptor populations, as well as an analgesic, antitussive, and sedative effects. The activity of tramadol is 1/10 - 1/6 of the activity of morphine. Unlike morphine, tramadol in therapeutic doses does not inhibit respiration, does not inhibit the motility of the gastrointestinal tract and does not affect cardiovascular activity. Paracetamol has an analgesic and antipyretic effect. The indications for use Ultram pill are acute and chronic pain syndromes of the strong and medium intensity of various origins (malignant tumors, injuries, severe neuralgia, and others). For short-term (five days or less) relief of acute pain, the recommended dose of the drug is 2 pills every 4-6 hours, but not more than 8 pills per day. Ultram side effects may include the following symptoms:: �On the part of the cardiovascular system: tachycardia, reduction in blood pressure (up to orthostatic collapse), syncopal states. �On the part of the gastrointestinal tract: nausea, vomiting, dry mouth, abdominal pain, anorexia, flatulence, constipation. �Nervous system and mental health: anxiety, incoordination, euphoria or depression, miosis, sleep disorders, increased nervous irritability, cognitive impairment, paresthesia, tremor, amnesia, convulsions, hallucinations, respiratory depression, sedation of different severity, dizziness, headache increasing muscle tone. �Urinary system: difficult or frequent urination. �Other: skin reactions (rash, pruritus, urticaria). Contraindications: �hypersensitivity to any of the components of the drug; �acute alcohol poisoning, analgesics, hypnotics, and psychopharmacological agents; �opioid addiction (opioid dependence); �disturbances of consciousness of unclear genesis; �violations of the respiratory center and respiratory functions, as well as in conditions �involving an increase in intracranial pressure, if the patient is not on artificial respiration; �brain diseases; �shock; �epilepsy or a tendency to convulsive seizures. �age up to 14 years.

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